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APIs Technology Platform
Drug Product Platform Technology

Physicochemical and Biopharmaceutical Characterization of Medicinal Compounds/Drug Substances Salt and Polymorph Screening Preclinical Animal Formulation Development and Their In Vitro and In Vivo Evaluation Poorly Soluble Drug Solubilization Technology Platform Liquid Dosage Form Platform Topical Dosage Forms Oral Dosage Forms Pediatric Dosage Forms

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“Poorly Soluble Drug Solubilization Technology Platform”

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Poorly Soluble Drug Solubilization Technology Platform

Langhua Pharmaceutical has established a comprehensive poorly soluble drug solubilization technology platform through collaboration with clients and its own investment in this field,. This platform enhances the dissolution rate and extent of poorly soluble drugs, improving absorption and ultimately increasing bioavailability and efficacy. To date, Langhua's pre-formulation team has successfully increased the bioavailability of many small molecule drugs using this platform.

Scope of Services

Solubilization via pH adjustment and in situ salt formation
Solubilization via microemulsion technology
Solubilization via nanocrystal suspension technology
Solubilization via complexation technology
Solubilization via Amorphous solid dispersion technology
Solubilization via mixed micelle technology
Solubilization via lipid emulsion technology
Solubilization via albumin bound nanoparticle suspension technology

The Key Advantages of the Platform

The advantages of our platform include reducing costs and development time. This is achieved by leveraging our in-depth knowledge of physical chemistry and solid-state chemistry to identify the root causes of poor solubility and/or poor dissolution of compounds. We then determine appropriate technologies to effectively enhance solubility and dissolution rates.